Support function for AUC integration
Usage
auc_integrate(
conc,
time,
clast,
tlast,
lambda.z,
interval_method,
fun_linear,
fun_log,
fun_inf
)Arguments
- conc
Measured concentrations
- time
Time of the measurement of the concentrations
- clast
The last concentration above the limit of quantification
- tlast
Time of last concentration above the limit of quantification (will be calculated, if not provided)
- lambda.z
The elimination rate (in units of inverse time) for extrapolation
- interval_method
The method for integrating each interval of
conc- fun_linear
The function to use for integration of the linear part of the curve (not required for AUC or AUMC functions)
- fun_log
The function to use for integration of the logarithmic part of the curve (if log integration is used; not required for AUC or AUMC functions)
- fun_inf
The function to use for extrapolation from the final measurement to infinite time (not required for AUC or AUMC functions.