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Simulated data set of concentration-time data for hydrocortisone.

Usage

hydrocortisone_sim_dose

hydrocortisone_sim_conc

Format

hydrocortisone_sim_conc is a data frame descrbing concentration-time with the following variables:

ID

Subject identifier

TIME

Time (in hours)

CONC

Plasma concentration of hydrocortisone (in ng/mL)

CONCU

Units for plasma concentration of hydrocortisone, "ng/mL"

hydrocortisone_sim_dose is a data frame describing dosing with the following variables:

ID

Subject identifier

TIME

Time (in hours)

TIMEU

Units for time, "hours"

DOSE

Dose of hydrocortisone (in mg)

DOSEU

Units for dose of hydrocortisone, "mg"

ROUTE

Route of administration

An object of class data.frame with 20 rows and 6 columns.

An object of class data.frame with 280 rows and 5 columns.

References

Derendorf H, Mollmann H, Barth J, Mollmann C, Tunn S, Krieg M. Pharmacokinetics and oral bioavailability of hydrocortisone. J Clin Pharmacol. 1991;31(5):473-6.