Pharmacokinetics of fluorouracil — fluorouracil • PKdata

Observed data set of concentration-time data for fluorouracil.

Usage

fluorouracil_conc

fluorouracil_dose

fluorouracil_demog

Format

fluorouracil_conc is a data frame describing concentration by time with the following variables:

ID: Subject identifier
TIME: Time (in minutes)
TIMEU: Units for time, "minutes"
NDOSE: Nominal dose (in mg/kg)
NDOSEU: Units for nominal dose, "mg/kg"
CONC: Plasma concentration of fluorouracil (in ug/mL)
CONCU: Units for plasma concentration of fluorouracil, "ug/mL"

fluorouracil_dose is a data frame describing dosing with the following variables:

ID: Subject identifier
NDOSE: Nominal dose (in mg/kg)
NDOSEU: Units for nominal dose, "mg/kg"
TIME: Time for start of dose (in minutes)
TIME_END: Time for end of dose (in minutes)
TIMEU: Units for time, "minutes"
ROUTE: Route of administration, "intravenous bolus"

An object of class data.frame with 48 rows and 7 columns.

An object of class data.frame with 8 rows and 7 columns.

An object of class data.frame with 8 rows and 17 columns.

References

MacMillan, William E., William H. Wolberg, and Peter G. Welling. 1978. "Pharmacokinetics of Fluorouracil in Humans." Cancer Research 38 (10): 3479-82.